Crouse Hospital has had a profound impact on the health of Central New Yorkers since its inception in 1887. Originally incorporated as a hospital specializing in women’s and children’s health, Crouse has been integral in improving public health in Syracuse. The tuberculosis epidemic in the late 19th and early 20th Centuries hit Syracuse particularly hard, and was a defining moment in the history of the hospital and in fighting tuberculosis. The Crouse Hospital Library Archives contains the records of Crouse-Irving Hospital, Syracuse Memorial Hospital their precursors and affiliated Schools of Nursing. This project curated by Alison Churchill in 2017 in fulfillment of requirements of a Masters in Public Health from SUNY Albany provides an opportunity to share Crouse’s public health history with particular emphasis on tuberculosis within the Central New York community, increase access of our tuberculosis-related materials, inform the public of Crouse Hospital’s historical impact on public health, and to make this era of public health history easily accessible for future researchers.