Items in New York Heritage are organized into collections, which provide additional context for understanding their significance and meaning.

The Crouse Hospital History collection contains black & white and colored photographs of Crouse Hospital and the staff and students who resided there from the late nineteenth through twentieth centuries.
A collection of images depicting the Rochester Dental Dispensary and School for Dental Hygienists in the early and mid-20th century.
The Lenox Memorial Hospital Collection contains documents and newspaper clippings about the hospital that served the area in the early to mid-twentieth century.
The Proceedings of the Rochester Academy of Science include original papers relating to the natural history of western New York State and biographical articles on the scientists who contributed to knowledge within this field. The abstracts of papers and posters presented at the annual Scientific Paper Session are included in issues as well. Topics range from the glaciology of the area, the water levels of Lake Ontario, to the flora of Bergen Swamp and Mendon Ponds Park. The Proceedings have been published on an irregular schedule since 1890.
This collection contains photographs sharing the history of the College of Saint Rose, including its students and faculty.

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