Items in New York Heritage are organized into collections, which provide additional context for understanding their significance and meaning.

The Canastota Schools Collection contains school souvenirs, including programs, newsletters and photos of Canastota students in the late nineteenth and early twentieth centuries.
A collection of photographs represent graduating classes of Albany College of Pharmacy from the late nineteenth to the early-twentieth centuries.
Collection of portraits, articles, memorabilia, and papers of Frances Folsom Cleveland Preston, with emphasis on her time at Wells College, in the White House, and her time in Aurora, NY as a Wells College trustee and wife of Thomas Preston.