Items in New York Heritage are organized into collections, which provide additional context for understanding their significance and meaning.

This collection contains several artifacts from the Robert L. Brown History of Medicine Collection, University at Buffalo, that highlight the life of Dr. Austin Flint. A renowned physician, Flint was one of the founding members of the University at Buffalo Medical School. As the most distinguished member of the founding faculty, he was named Professor of Principles and Practice of Medicine and Clinical Medicine, and he served as the first registrar and treasurer. In addition to his work at the medical school, he authored more than 200 articles and 16 books. Many of his articles were published in the "Buffalo Medical Journal", a journal that he himself founded.
Elizabeth Blackwell (1821-1910) was the first woman in the world to graduate from medical school and become a physician. The collection includes images of Dr. Blackwell and her writings dating to the late 19th century
Photographs and documents relating to Good Shepherd Hospital in Syracuse, New York, throughout its existence from the late-19th century to mid-20th century.