Items in New York Heritage are organized into collections, which provide additional context for understanding their significance and meaning.

Photographs relating to the history of Rochester General Hospital during the late 19th and early 20th centuries.
Photographs and documents relating to the Syracuse Free Dispensary which operated from 1888-1964.
Photographs, historical objects, memorabilia and ledgers from 1887 to the 1990s reflecting the history of Vassar Brothers Medical Center.