Items in New York Heritage are organized into collections, which provide additional context for understanding their significance and meaning.

Historic images of people, places, and events in the town of Marlborough.
Photographs, correspondence, and newspaper clippings relating to the early campuses of the Syracuse University College of Medicine in Syracuse, New York in the late 19th and early 20th century.
The Network of Religious Communities (NRC) is an inter-religious/ecumenical organization of denominations and religious organizations located in Western New York. The NRC has collected meeting minutes, correspondence, directories and other projects from the predecessor organizations that date back from 1857 through the current times. Among the topics covered are religious education, ecumenicalism, community relations, and social welfare.