Items in New York Heritage are organized into collections, which provide additional context for understanding their significance and meaning.

The Sherwood Collection is mainly comprised of letters to and from Samuel Sherwood (1779-1862), his second wife Laura Bostwick Sherwood (1790-1863), and members of their family.
This collection contains documents relating to prescription drugs and Dr. Best.
A photograph collection from the late 19th to early 20th centuries, documenting hydro-electric power industry in Niagara Falls, NY
Photographic postcards documenting the town of DeRuyter and surrounding areas in the early to mid-20th century.